Ageing or aging is the process of becoming older until our bodies can no longer function properly and will stop working at some point.The most accepted theory, to this date, is that aging is the accumulation of damage that happens to the body of living things as time progresses, and their lives keep going until there is enough damage that they can no longer resist.This “accumulation of damage” is what causes cells, organisms and whole systems of the body to fail, while there also exist internal causes of damage that help deteriorate the tissues of the body over time.However, an extensive study of the doctor Mikhail V. Blagosklonny has shown that this is not actually the case, but something completely different might be the cause of cancer as we know of it today.
According to his studies, aging is not an accumulation of damage, but it is a continuation of the process of growth that is experienced in the youth of men and women.As life progresses, the bodies of living beings grow as much as their DNA dictates, and their alimentation provides, but the DNA also dictates when the growth stops happening and the systems of the body start moving towards a period of life where deterioration happens naturally. One can live their lives eating healthily and not having external damage at all, but their body will still age because it is the natural course of what happens to all living beings.With these discoveries, however, Dr. Mikhail V. Blagosklonny has furthered his research into developing the next-gen anti-aging drug. As much as it sounds fantastic and utopic, the expert is actually reaching positive results to what might be the first remedy that actually slows down aging and prevents diseases that come with the process.
According to the specialist, the hyperfunction theory, as he likes to call it, allows scientists to now understand where the aging code comes from, and it can be traced back to signaling pathways such as what they call “TOR,” which stands for “Target of Rapamycin,” the name of the drug that is the scientist Blagosklonny developed Oncotarget .While it is an anti-aging drug of sorts, people might think that this is will make humans have some sort of immortal beings. Dr. Mikhail V. Blagosklonny addresses this issue when he explains that the drug he is developing simply slows down aging to abolish diseases like cancer that happen to old people more than younger ones. These diseases will not be the causes of death anymore, at least not of the same magnitude that it has been for years, but there will always exist additional events that cause the death of individuals.The TOR-Centric Model, which comprise the pathway that is essential for the growth and development of human beings, can be found in three different sources currently. The first one being the person’s genetics; the second being the cellular senescence (when the cycle of our body cells is blocked) because the rapamycin suppresses geroconversion. The third and last source of the TOR-Centric model are diseases like Parkinson and Alzheimer, for the surprise of most scientists.Today, Dr. Mikhail V. Blagosklonny is still furthering his researches to find out more about aging and the diseases that come with it.
Yanni Hufnagel’s fortitude for aligning great talent with the tenacity to win has become his most-influential asset to the teams he’s been accepted to be a part of.
In 2009, Yanni Hufnagel became the assistant coach and recruiter for the Harvard Crimson men’s basketball program. In 2013, Yanni became the assistant coach for Vanderbilt Commodores which he is credited with helping the team become the 29th ranking recruiting class in 2014. During his tenure, he was considered very influential with the players; most notably Wade Baldwin and Matthew Fisher-Davis both of whom Yanni personally mentored to further their basketball career. The team had a stellar year-ending record of 21-8 which established a record for the school’s wins.
By the end of 2014, Yanni Hufnagel was offered and accepted the assistant coaching and recruiter position with the California Golden Bears after the successful tenure with Vanderbilt. As the recruiter, Yanni persuaded up and coming basketball stars Jaylen Brown and Ivan Rabb to join the team which helped lead the Golden Bears to the 2016 NCAA Tournament.
His trusted relations with those of whom he’s coached are a testament to Yanni Hufnagel’s ethics and moral compass for doing the right thing on behalf of the players, and the team. The players, and the head coaches, believe in Yanni’s core values which bring credibility to the game of basketball. He’s been a great mentor to young players who respect him immensely.
In addition to mentoring those with whom he also enthusiastically coaches, Yanni Hufnagel has been very active in working alongside the Partners for Youth with Disabilities within their Mentor-Match program. The program was created in 1985 with a goal of helping young people with disabilities reach their highest potential for independence. Yanni works with the youth monthly to help with development and personal goals.
The Ubuntu Education fund was able to raise £600,000 at a charity fund gala that was held in London. Andrew Rolfe organized the gala. The funds will be directed towards helping underprivileged children. The funds will go towards the expansion of the Port Elizabeth campus of the Ubuntu Education Fund and the renovation of the pediatric clinic. They were able to surpass the target of six hundred thousand pounds by £3000. The gala was attended by popular philanthropist and celebrities in London. Rolfe welcomed the guests. They were treated to a performance of Xhosa chorales. Sinesipho Rabidyani captured the audience with a scintillating story about the Ubuntu Education Fund that had impacted her.
Sinesipho said that she dreaded going home each day because her father had a drinking problem. Sinesipho studied hard and was accepted as an Ubuntu Fund scholar. Her story inspired people to donate generously at the charity gala. This allowed them to meet their goal. Andrew Rolfe is the chairman of the board of the Ubuntu Education Fund. Rolfe studied Politics, Economics, and Philosophy at Oxford University before attaining a Master’s in Art from the university. He has a Master’s in Business Administration from the Harvard Business School.
Andrew joined PepsiCo as the vice president after completing his MBA. Rolfe served in this role for five years. He left to join Pret A Manger as the chief executive officer and the chair of the board. Rolfe is credited with transforming Pret A Manger into an international retailer. He worked at the company until 2004. He was later appointed the President of Gap International. He was involved with helping the brand to expand internationally and to implement growth strategies. Rolfe was the president of the company for two years.
Rolfe has been the managing director of Towerbrook Capital Partners since the start of 2006. He is also the Head of US Private Equity at the firm. He was appointed the Director of J. Jill Inc. in May 2015. He is the director of several companies including True Religion Apparel, Kaporal Jeans, the Jimmy Choo Group, and Wilton Industries.
Omar Yunes, a Mexican entrepreneur who runs Sushi Itto restaurants in his home country, was recently named the best franchisee during the Best Franchisee of the World (BFW). The glamorous award ceremony was held in Florence, Italy. Mr. Yunes won the award for the contribution that he has made towards establishing Sushi Itto among the most popular brands in the Mexican hospitality sector.
Omar is among the youngest franchisees in Sushi Itto’s history having signed up at the age of 21 years. Despite his young age, he had a clear goal in mind when he started out. He currently runs 13 franchise units located in Vera Cruz, Puebla, and Mexico City. These account for nearly ten percent of the total number of outlets that operate under the Sushi Itto brand.
Criteria for Selection
Upon receiving his award, Omar was quick to assert that he would not have won it had it not been for his employees’ input. The 13 units that he runs employs more than 400 employees. The 2015 BFW Awards were graced by representatives from more than 34 countries including Argentina, Mexico, Italy, Brazil, France, Hungary, and Portugal.
The criteria for selection was the effect that franchises have on the network rather than the brand. This included the contributions made in terms of employee motivation, knowledge, and improvements made to the original business model.
Sushi Itto’s CEO Benjamin Cancelmo asserts that the awards are a manifestation of the brand’s effort to offer excellent customer service and a unique flavor of hospitality. It similarly proves that Mexican franchises are no longer a regional affair as it used to be in the past.
Omar Yunes in Brief
Yunes is a shrewd investor with deep interests in the real estate and hospitality market. He began his entrepreneurial career at a relatively young age and therefore, had to overcome numerous challenges to get to where he is today. His name is synonymous with the success that the Mexican franchise of Sushi Itto has attained in the past few years. He also has extensive holdings in the lucrative New York property market. Omar spends his free time looking for interesting investment opportunities.
Eric Paul Lefkofsky is a Chicago based entrepreneur, philanthropist and author. He began his entrepreneurial journey in 1993, after graduating from the University of Michigan where he studied law. Lefkofsky, together with his friend, Brad Keywell, began a company called Brandin Apparel where they sold carpets to their friends and college mates. The success of this venture gave him hope and a strong conviction that he could make it in the aggressive health care business world. He went ahead to launch various other companies like Groupon where he acted as its chairman and chief executive officer and Staberbelly. He also launched InnerWorkings in 2001 and Echo Global Logistics in 2005. The company was led with so much charisma and success that it attracted the New Enterprise Asociates and later on went public on NASDAQ.
Lefkosky’s greatest achievements is seen through the risk he took to begin a health company called Tempus. Having little knowledge on medicine and health, he began reading books and partnered with the right people to begin Tempus. Tempus is a tech company that provides solutions to doctors and physicians to help cure cancer. The company collects data and analyses it, after which the data is availed to the physicians who use it to help their patients who may be suffering from similar cases or tumour. Since its initiation in 2015, Lefkofsky has been the chief operating officer and its cofounder and has used his entrepreneurial skills to keep organization running, profitable and impactful to the society.
Lefkosky and his family are also popularly known for their commitment to helping their communities and impacting lives. Lefkofsky is engaged in various charity organizations where he spends both resources and time in. he began the Eric Lefkofsky Foundation in 2006, which is purposed to support organizations that are involved in charity science and education courses. He also supports and funds the Giving Pledge charity organization that is determined to provide food, clothing, shelter and medical supplies to those in need.
Lefkofsky is a man of many talents. Besides being a great leader, humanitarian he has also authored a book called the Accelerated Disruption which gives leaders insights on management of their businesses.
In Regard To Eric Lefkofsky: adrinkwith.com/eric-lefkofsky/
Betsy DeVos knows that kids that are part of the charter school system are going to be much more equipped to handle standardized testing and college courses. She believes that school should be something that kids look forward to because they are learning new things in an exciting manner.Betsy DeVos is a longtime philanthropist to the education system, and I think people are going to see a lot more from her because her work is getting recognized now that she is the Secretary of Education. People really have to be aware of how the education system is working right now and they have to know that Betsy is someone that is actually a looking for a chance to make improvements in the system.
She is not planning to sit in an ivory tower and judge educators. Instead, she plans to get out into the education environment and do some things that can change the structure of learning for kids that may have become victims to a lack of enthusiasm by teachers. There’s nothing worse in the school system than a bored teacher and Betsy DeVos knows this. She realizes that there has to be a high standard that is put in place in order to get students to really take any interest in what is going on in the classroom. She knows that this cannot happen if the teachers are motivated so she is working on the possibilities of getting higher incomes for the teachers. She also realizes that students are not going to be stimulated if they do not have a level foundation.
That is why she is starting all the way from the first grade school system model and working her way up to the high school kids and seniors. She knows that there is a lot that needs to be done for education, and the improvements that she makes will be something that can totally transform how America does when it comes to standardized testing and general job improvement. Betsy DeVos realizes that education plays a great part in how students are able to achieve when they are older.Lots of children in school systems today are definitely going to benefit from what Betsy DeVos (@ Besty DeVos) Twitter has put in place. She is helping so many kids that are becoming aware of just what it means to get a quality education. DeVos has been a philanthropist that has focused on putting her money towards education and making sure that the art programs stay within the school system. I think that she and her husband are both doing a commendable job in their giving, and I believe that her role as the Secretary of Education will be equally important.
Agora Financial is helping people find a better sweet spot when it comes to investing. Most investors do not know how much money it takes to build a successful portfolio. The average investor may not even have a clue as to what they want to invest in. With Agora Financial people have a better clue about what they should be putting their money into.
Investors that are not able to maximize their returns are never going to be fully sure about how much money they need to save. When people are able to tap into a financial publications source like Agora Finance they have a better clue about the money that they need to put aside. They have much better access to the market trends and the way that the market works. The only way that people can truly track their gains and losses is by paying attention to the market.
People have to be aware of the economic factors that are going to change what is happening inside of the stock market. Agora Financial has experienced consultants in place that can help anyone that maybe looking for guidance. Agoura Finance has people in places that are going to help them find those investment opportunities that are still on the ground floor. This is great for someone that is trying to invest early.
Anyone that has a strategy for wealth management will know that it is going to take a lot of creativity to diversify the portfolio. Stocks are good, but stocks are just the beginning of the investment process. Index funds and mutual funds are also valuable. People are also going to take interest in the annuities that are available for investments. Agora Financial aligns investors with the different industries that are going to thrive from year to year.
For more information follow Agora Financial on Twitter.
George Soros has proven to be one of the finest progressives in America, and he is offering money from his own pocket to help pay for what he believes is right. He has been reported by Politico As having helped a number of people peacefully protest oppression and brutality. This article explains how George Soros is giving his money to serve the greater good in as many ways as possible.
#1: Giving To Progressive Causes
Giving to progressive causes is a major taking point for George, and he offers his money to charities and causes that he believes in most. He knows that the people who benefit from these charities are thankful, and he wants them to know that they have a backer who will support their means of protest. He runs the Open Society Foundation, and he is bringing together progressive donors to give to some of the biggest campaigns in the world. Read his profile at Business Insider.
#2: Why Does He Give Back?
George gives back to progressive causes because he knows that these charities need all the help they can get. He runs the Open Society Foundation to help people who are in oppressed areas, and he is hoping that his progressive donors will give their money to causes that will change the landscape of American politics. He did not survive the holocaust to come back to a world that is much like Nazi Germany, and he hopes that he can stop the tide from leaning in that direction.
Read more: http://www.forbes.com/profile/george-soros/
#3: Giving Millions To Campaigns
The campaigns that George Soros gives to will be those that hope to push liberal agendas, and he wants to be as progressive as possible with his money and time. He knows that lives will change because of the work that he has done, and he knows that he has the money to affect change over a large swath of society. There are many people who will feel a change in their lives, and they will see that he has given back to the people that need it most. He wants to see people elected who will fight for them on every level.
There are many people who have seen their lives changed by George Soros, and he is giving back to communities that are in need of assistance from his pocket. He wants to ensure that there is not a a conservative agenda that takes over the world, and he wants to see the progressive ideals that came out of his family give back to more people. Someone who has been oppressed may trust in George, and he someone who is in danger of persecution may turn to George and the many causes he has given back to. Learn more about this article at washingtontimes.com.
One of the most useful and productive tech enhancements over the past decade has been the development of cloud-based technology. Today, millions of individual and companies are able to use cloud storage systems to manage their SQL databases. This helps to reduce the physical needs for large servers and can also make systems more accessible for people across the world. Today, one of the leading cloud service providers is
NuoDB is a company in the database industry that is based in Cambridge, Massachusetts. The company was founded nearly 10 years ago and has quickly grown to be one of the most reputable developers of cloud technology in the industry. They have received a range of professional recognitions and have a large group of corporate clients that include Kodiak, the UAE Exchange, and Alfa Systems.
What helps to make NuoDB such a large member of the industry is the fact that they stay ahead of technology. Today, they are considered an elastic database that is available for cloud-based applications. The benefit of their system is that they database system can actually become more efficient when new databases and systems are added to the cloud. This can be very encouraging to clients that are looking to incorporate the technology.
Amicus Therapeutics is a young company which was created at the beginning of 2002. It is based in the city of Cranbury, New Jersey, and its industry is biopharmaceutics. The company currently has more than a hundred people in its workforce. The leader of the Amicus Therapeutics is Mr. John F. Crowley who is at the position of the chief executive officer (CEO). Mr. John F. Crowley has been the chief executive officer of Amicus Pharmaceuticals since the year of 2005. Five years later in 2010, Mr. John Crowly assumed the post of Chairman of the Board succeeding Mr. Donald Hayden, Jr.
Amicus Therapeutics has a focus on lysosomal storage disorders which is a collective term for a number of rare and orphan diseases. Amicus Therapeutics develops products through a system that vastly depends on the platform of CHART® – Chaperone-Advanced Replacement Therapy. This platform concentrates on the development of enzyme replacement therapies.
Over the years the company of Amicus Therapeutics has expanded through therapy development and acquisitions as well. The company indeed picked up the pace and was recognized a few years ago in 2014. It was noted for supposedly having one of broadest of portfolios in the industry regarding small molecule pharmacological chaperones. Amicus Therapeutics has been collaborating with some other companies such as Shire, JCR Pharmaceutical, GlaxoSmithKline, and more. Some of the partnerships lasted up to three years.
The acquisition of Amicus Therapeutics started up in 2013. That year was a winning one for Amicus Therapeutics as it acquired one of its competitors – Callidus Biopharma. That allowed Amicus Therapeutics to become a proprietor of the treatment for the Pompe Disease which is based on an enzyme replacement therapy. In September 2015, another acquisition followed. Amicus Therapeutics bought Scioderm for nearly a billion dollars as well as stock. That expanded Amicus Therapeutics and provided a clearer way ahead.
Amicus Therapeutics currently has a few medications on the market. The company mostly focuses on research. It expanded and set up another study site inSan Diego in 2008. The work was going smoothly up until the year, but after a while, the company was back on its feet and better than ever.